Abstract
EBV-positive diffuse large B-cell lymphoma of the elderly is a newly described aggressive lymphoma predominantly affecting patients >50 years of age. Patients may present with nodal and/or extranodal involvement. The lung is one of the more common extranodal sites. The incidence of pleural fluid involvement is less well described. In one study by Oyama et al., pleural effusions were noted in nine percent of cases. Identification of pleural fluid involvement could be important as it may carry prognostic importance in staging (it typically occurs more often in cases with widespread disease), and it could be a relatively easy means of establishing a diagnosis in newly presenting cases. We report the first description of the pleural fluid cytology in a case of EBV-positive diffuse large B-cell lymphoma of the elderly.
Highlights
EBV-positive diffuse large cell lymphoma (EBV+ DLBCL) of the elderly is a newly recognized aggressive B-cell lymphoproliferative disorder
While pleural effusions have been noted in these patients, the cytologic features have not been described
Identification of pleural fluid involvement may provide a rapid diagnosis as well as assist in staging the tumor. This is the first description of the cytologic features of pleural fluid involved by EBV+ DLBCL of the elderly
Summary
EBV-positive diffuse large cell lymphoma (EBV+ DLBCL) of the elderly is a newly recognized aggressive B-cell lymphoproliferative disorder. Unlike other EBV-associated lymphomas, EBV+ DLBCL of the elderly occurs exclusively in patients with no history of immunodeficiency. While pleural effusions have been noted in these patients, the cytologic features have not been described. This is the first description of the cytologic features of pleural fluid involved by EBV+ DLBCL of the elderly.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
