PLEURAL EFFUSIONS DUE TO SARS-COV-2 INFECTION

Abstract

SESSION TITLE: Chest Infections Posters SESSION TYPE: Original Investigation Posters PRESENTED ON: October 18-21, 2020 PURPOSE: The radiological changes in the lungs of patients infected with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) have not been fully characterized, but different radiological patterns have been observed at different times throughout the disease course. Pleural effusions range between 5% and 9.7% of the patients with confirmed COVID-19 pneumonia. In this study we aimed to calculate the prevalence of pleural effusions in COVID-19 hospitalized patients and to objectively describe the pleural fluid characteristics in this subgroup of patients. METHODS: Retrospective medical records review of patients diagnosed with pleural effusions and SARS-CoV-2 between January 1, 2020 and May 20, 2020 at Beth Israel Deaconess Medical Center, Boston, MA. Patients were identified from our institutional database. Demographics, baseline comorbidities, mortality, intensive care unit (ICU) stay, interventions and pleural fluid analysis (PFA) were recorded. RESULTS: A total of 587 patients were admitted with SARS-CoV-2 infection (Age 65.29 years [SD 16.9]; 49.9% males). Nineteen (3.2%) developed pleural effusions during hospitalization course. There was no statistical difference between the baseline characteristics of both groups. Patients who developed pleural effusions had a prolonged ICU stay (7 vs 2 days, p=0.01). There was no statistically significant increased mortality rate in the pleural effusions group. Six (31.6%) of patients with pleural effusions required fluid drainage with tube thoracostomy. All PFA of the six patients were non complicated neutrophilic exudates. CONCLUSIONS: Pleural effusions are an infrequent finding in patients with COVID-19. Most effusions are small and don’t require drainage. Pleural effusions may not be associated with an increased mortality in COVID-19 patients, but further prospective large cohort studies are needed. CLINICAL IMPLICATIONS: Characterization of pleural effusions in COVID-19. DISCLOSURES: No relevant relationships by Ramsy Abdelghani, source=Web Response No relevant relationships by Alvaro Ayala, source=Web Response No relevant relationships by Alex Chee, source=Web Response No relevant relationships by Fayez Kheir, source=Web Response Consultant relationship with Boston Scientific Please note: $1001 - $5000 by Adnan Majid, source=Web Response, value=Consulting fee Consultant relationship with olympus Please note: $5001 - $20000 by Adnan Majid, source=Web Response, value=Consulting fee Consultant relationship with pinacle biologics Please note: $1001 - $5000 by Adnan Majid, source=Web Response, value=Consulting fee Consultant relationship with cook medical Please note: $1001 - $5000 by Adnan Majid, source=Web Response, value=Consulting fee No relevant relationships by Rachel Martinez, source=Web Response No relevant relationships by Mihir Parikh, source=Web Response No relevant relationships by Priya Patel, source=Web Response No relevant relationships by Alichia Paton, source=Web Response No relevant relationships by Juan Pablo Uribe, source=Web Response