Abstract
Milroy's disease is a congenital familial type of lymphedema which generally involves only the lower extremities up to the inguinal ligament. Letessier in 1865 was the first to report the condition in an account of 4 cases of lymphedema in a single German family. Milroy in 1892 reported 22 cases of an “undescribed variety of hereditary edema” in 6 generations of a single family. In 1899 Meige described an additional 8 cases in a French family. In these 8 cases, however, the onset of edema occurred at puberty rather than at birth. In spite of a considerable amount of literature concerning the disease since that time, we have been unable to find any published report of pleural effusion in association with chronic hereditary lymphedema. Case Reports Case I: E. F., a 44-year-old white male, had suffered from edema of both legs since birth, as had his mother and one sister (Case II). The mother died in 1923 at the age of thirty-three from “septic poisoning.” No previous cases of lymphedema were known to have o...
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