Pleural and Pulmonary Solitary Fibrous Tumours: Our Experience With This Rare Tumour

Abstract

Purpose: Solitary Fibrous Tumours(SFT) are a rare entity with a frequency of occurrence of SFTs arising from the pleura estimated at 2.8 per 100,000. We report our experience with the clinico-pathological characteristics, management and outcomes of treatment of pleural and pulmonary solitary fibrous tumours over the past eleven years. We also present an overview on solitary fibrous tumours of the lung and pleura based on the existing literature. Methodology: Clinical notes and investigations of patients operated for solitary fibrous tumours of the lung and pleura between 2005 and 2015 were retrospectively reviewed. A literature review on this condition was done. Results: Thirteen patients (7 male and 6 female) underwent surgical treatment of pleural / pulmonary SFTs between 2005 and 2015. The mean follow-up was 41 months. There was no in-hospital / 30 day mortality. Only 800 cases have been reported until 2002. Though there is no clear demarcation between benign and malignant tumours, a mitotic rate of > 4 mitoses per 2 mm squared is the most reliable indicator of aggressive behaviour. Conclusion: Pleural / pulmonary SFTs are rare tumours which are often asymptomatic. Complete surgical excision offers the best prospect of cure. Regular long-term radiological surveillance provides the best chance of detecting and treating recurrences early.