Abstract

The plethysmographic peripheral perfusion index (PPI) is a very useful parameter with various emerging utilities in medical practice. The PPI represents the ratio between pulsatile and non-pulsatile portions in peripheral circulation and is mainly affected by two main determinants: cardiac output and balance between sympathetic and parasympathetic nervous systems. The PPI decreases in cases of sympathetic predominance and/or low cardiac output states; therefore, it is a useful predictor of patient outcomes in critical care units. The PPI could be a surrogate for cardiac output in tests for fluid responsiveness, as an objective measure of pain especially in un-cooperative patients, and as a predictor of successful weaning from mechanical ventilation. The PPI is simple to measure, easy to interpret, and has continuously displayed variables, making it a convenient parameter for detecting the adequacy of blood flow and sympathetic-parasympathetic balance.

Highlights

  • AND AIM OF THE WORKThe pulse oximeter is a basic monitor in medical practice with an essential role to evaluate the peripheral oxygen saturation and heart rate using plethysmography technology

  • The peripheral perfusion index (PPI) decreases in cases of sympathetic predominance and/or low cardiac output states; it is a useful predictor of patient outcomes in critical care units

  • The PPI could be a surrogate for cardiac output in tests for fluid responsiveness, as an objective measure of pain especially in un-cooperative patients, and as a predictor of successful weaning from mechanical ventilation

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Summary

Frontiers in Medicine

The plethysmographic peripheral perfusion index (PPI) is a very useful parameter with various emerging utilities in medical practice. The PPI represents the ratio between pulsatile and non-pulsatile portions in peripheral circulation and is mainly affected by two main determinants: cardiac output and balance between sympathetic and parasympathetic nervous systems. The PPI decreases in cases of sympathetic predominance and/or low cardiac output states; it is a useful predictor of patient outcomes in critical care units. The PPI could be a surrogate for cardiac output in tests for fluid responsiveness, as an objective measure of pain especially in un-cooperative patients, and as a predictor of successful weaning from mechanical ventilation. The PPI is simple to measure, easy to interpret, and has continuously displayed variables, making it a convenient parameter for detecting the adequacy of blood flow and sympathetic-parasympathetic balance

AND AIM OF THE WORK
PPI AS SEVERITY INDICATOR IN CRITICALLY ILL PATIENTS
PPI AS A GUIDE FOR FLUID THERAPY
PPI AS AN OBJECTIVE MEASURE FOR PAIN
PPI IN THE OPERATING ROOM
OTHER USES OF PPI IN CRITICALLY ILL PATIENTS
LIMITATIONS
Findings
AUTHOR CONTRIBUTIONS
Full Text
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