Abstract

Salivary gland tumors are a relatively rare and morphologically diverse group of lesions. Pleomorphic adenoma is a benign tumor of the salivary gland that consists of a combination of epithelial and mesenchymal elements. The tumor most commonly arises from the parotid (60-70%) or submandibular glands. It develops less frequently in a minor salivary gland, presenting as an intraoral mass depend on the soft palate. We describe a case of benign pleomorphic adenoma of soft palate in a 45 year old female with computed tomography and histopathological findings. This patient presented in ENT department with history of gradually increasing mass lesion in the palatal region over a period of few months.

Highlights

  • Pleomorphic adenoma is the most common tumor (60%) of major and minor salivary glands, nearly 70% of the tumors of minor salivary glands are Pleomorphic adenomas, and the most common intraoral site is the palate, followed by upper lip and buccal mucosa [1]

  • Studies have reported that in world population 13.9-51.4% of all salivary gland tumors arise from an intraoral site and 34.7-67.1% of them are benign [2]

  • We report a case of a pleomorphic adenoma with predominant plasmacytoid myoepithelial cells arising in minor salivary glands of the soft palate in a 45 year old female

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Summary

Introduction

Pleomorphic adenoma is the most common tumor (60%) of major and minor salivary glands, nearly 70% of the tumors of minor salivary glands are Pleomorphic adenomas, and the most common intraoral site is the palate, followed by upper lip and buccal mucosa [1]. The lesion appeared to arise from mid part of palate, extending up to the posterior border of hard palate (Figure 1) It was non-tender, firm, and non compressible and had well defined margins. On the basis of history and clinical examination a diagnosis of solid non infectious mass of soft palate likely of benign etiology was made. The possibility of infective etiology (palatal abscess) was less likely as there no fever neither there was any tenderness or erythema She was advised a contrast enhanced computed tomography scan of paranasal sinuses. The CT scan revealed a well defined homogeneously enhancing hypodense soft tissue les ion of size 4,27 cm X 4cm X 4,5 cm arising from right side of soft palate and abutting the hard palate anteriorly, uvula posteriorly, tongue inferiorly and nasopharyngeal wall superiorly. No recurrence was observed after a follow-up period of 1 year

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