Abstract
Purpose:To describe the clinical presentation and treatment of a patient with a cutaneous pleomorphic adenoma of the eyelid.Case Report:A 73-year-old male patient presented with a nodular mass on the lateral third of his right upper eyelid, which had slowly enlarged over 10 years. Radiologic features were of an extra-conical mass, with no invasion of adjacent structures. An excisional biopsy of the lesion was performed. The histopathological examination revealed a biphasic tumor, composed of tubules with a double layer of epithelial cells arranged in a chondromyxoid stroma. The inner epithelial cells were positive for pancytokeratins AE1/AE3 and carcinoembryonic antigen. The outer epithelial cells and stromal component expressed vimentin and S100 protein. These pathologic findings were consistent with a palpebral pleomorphic adenoma, with an apocrine gland origin.Conclusion:Pleomorphic adenomas of the skin are rare tumors, and even less frequent as tumors of the ocular adnexa. These lesions should be considered in the differential diagnosis of palpebral nodular masses, and complete excision should be attempted due to the possibility of malignant transformation.
Highlights
Pleomorphic adenoma (PA), known as chondroid syringoma, is a tumor that arises most often in the lacrimal or salivary glands.[1]
Histopathological and immunohistochemical analyses are essential for a definite diagnosis since they are characteristic for skin PA and permit a differential diagnosis with more frequent PA of the lacrimal gland
We report a case of pleomorphic adenoma which originated from the ocular adnexa with important clinical implications for management and follow‐up
Summary
Pleomorphic adenoma (PA), known as chondroid syringoma, is a tumor that arises most often in the lacrimal or salivary glands.[1]. Pleomorphic adenoma of the eyelid with apocrine gland origin; an atypical location. Pleomorphic Adenoma of the Eyelid; Rothwell et al
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