Abstract

Wearable sensors have received a major recent attention owing to their considerable promise for monitoring the wearer's health and wellness. The medical interest for wearable systems arises from the need for monitoring patients over long periods of time. These devices have the potential to continuously collect vital health information from a person's body and provide this information to them or their healthcare provider in a timely fashion. Unlike early efforts aimed at monitoring mobility and vital signs, our recent efforts aim at filling the gaps by providing continuous biochemical information. The new chemical sensing wearable platforms provide new avenues to continuously and non-invasively monitor individuals and can thus tender crucial real-time information regarding a wearer's health. This presentation will discuss recent developments in the field of wearable electrochemical sensors integrated directly on the epidermis or within the mouth for various non-invasive biomedical monitoring applications [1-3]. Particular attention will be given to non-invasive monitoring of metabolites and electrolytes using flexible amperometric and potentiometric sensors, respectively, along with related materials, energy and integration considerations. Microneedle sensor arrays for multiplexed ISF monitoring will also be discussed also with wearable energy harvesters aimed to power these devices. The preparation and characterization of such wearable electrochemical sensors will be described, along with their current status and future prospects and challenges.REFERENCES[1] "Wearable Chemical Sensors: Present Challenges and Future Prospects" A. J. Bandodkar, I. Jeerapan, J. Wang, ACS Sensors, 2016, 1, 464.[2] A. J. Bandodkar and J. Wang, "Non-invasive wearable electrochemical sensors: a review", Trends Biotechnol., 2014, 32, 363.[3] "Wearable biosensors for healthcare monitoring", J. Kim, A. S. Campbell, B. Esteban-Fernández de Ávila, and J. Wang, Nature Biotechnology, 2019, 37, 389.

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