Abstract
In recent years, great interest has been shown in platinum blues. This interest has been mainly focused on their potential antitumor activity and low nephrotoxicity compared with the anticancer drug cisplatin. We now describe the synthesis of new crystalline platinum creatinine complexes and particularly their chromophore derivatives, the properties of which substantially enhance out understanding of this interesting class of compounds. Creatinine has been chosen as ligand because of its importance in clinical chemistry and its similarity to 2-pyrrolidone which is structurally characterized in platinum tans. The intriguing colors observed in solution depend upon the anion present, and their stability with time at ambient temperatures has been a very important fact in facilitating this study by UV-Vis.
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