Abstract
Abstract: Lung cancer is the leading cause of malignancy in the world reaching up to 13% of all cancer diagnoses. Platelet-to-Lymphocyte Ratio (PLR) and Neutrophil-to-Lymphocyte Ratio (NLR), are promising markers of inflammatory prognosis, clinical decisions for proper management of lung cancer patients. The research used a retrospective analytic observational study as its research method. Samples were taken from Pathology Anatomy Laboratory, and the medical record data of lung cancer patients in Ulin General Hospital Banjarmasin from 2017 to 2018. Male lung cancer patients have percentage of 72% with PLR NLR values by sex are not much different p>0.05. 23% of patients were aged ≥ 65 years and 77% were aged £ 65 years with value p>0.05. Adenocarcinoma reaches 65% with p>0.05. Most metastases are 44% pleural effusion with value p>0.05. Percentage of advanced stage is 90% with a higher PLR NLR value at the end stage. There is a meaningful relationship of NLR with lung cancer stage p<0.05, but no relantionship with PLR p>0.05. PRL and NRL are increased at advanced stage. NRL and PRL did not differ significantly based on age, sex and histology of lung cancer. Keywords: Platelet-to-lymphocyte ratio (PLR), Neutrophil-to-lymphocyte ratio (NLR), lung cancer
Highlights
Lung cancer is the leading cause of malignancy in the world reaching up to 13% of all cancer diagnoses
The incidence of lung cancer is quite high in Indonesia, which is ranked 3rd of all malignant neoplasms in inpatients and outpatients in hospitals, in 2012, lung cancer accounted for about 23.1% of all new cancer cases and was the cause of 19.7 % of all cancer deaths in Indonesia.[1]
Inclusion criteria include all patients diagnosed with histological lung cancer, inpatients at Ulin General Hospital Banjarmasin from 1 January 2017 to 31 December 2018 and not having hematological abnormalities such as: diseases that affect the production of blood cells in the bone marrow and Pulmonary infection diseases such as: Pulmonary TB, Pneumonia, Bronchitis, Lung Abscess and Lung Mycosis
Summary
Lung cancer is the leading cause of malignancy in the world reaching up to 13% of all cancer diagnoses. PLR is calculated as a ratio of the platelets number to the lymphocytes number. NLR is calculated as the ratio of the neutrophils number to the lymphocytes number.[2,3]. In this study the PLR and NLR profiles of lung cancer patients in the Ulin General Hospital Banjarmasin in the January 2017-December 2018 period will be explained. The parameters observed were neutrophil, platelet and lymphocyte values. Inclusion criteria include all patients diagnosed with histological lung cancer, inpatients at Ulin General Hospital Banjarmasin from 1 January 2017 to 31 December 2018 and not having hematological abnormalities such as: diseases that affect the production of blood cells in the bone marrow and Pulmonary infection diseases such as: Pulmonary TB, Pneumonia, Bronchitis, Lung Abscess and Lung Mycosis. The obtained data was recorded and processed using SPSS 16.0
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
