Abstract
Platelet survival studies were performed in three groups of males: 10 healthy young students, 8 healthy middle‐aged men and 8 haematologically normal subjects with mild to moderate cardiovascular diseases. Two mathematical functions were used in order to obtain platelet mean life span. (MLS) according to the principle of Mills (1946). The two functions were equivalent for the estimation of platelet MLS. In all groups studied, the range for platelet MLS was wide, but was most pronounced in the group of subjects with cardiovascular diseases. The mean platelet MLS for young students was higher than the mean for healthy middle‐aged men, and the mean for the latter was higher than the mean platelet MLS in the group of subjects with cardiovascular diseases. The differences between these three groups were, however, not statistically significant. The means for platelet destruction rate and turnover were equal in the two groups of healthy volunteers studied. In the group of subjects with cardiovascular diseases the mean for platelet destruction rate and turnover exceeded the means for healthy volunteers but not significantly so.
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