Abstract
Platelet Rich Fibrin (PRF) is a blood concentrate with a fibrin matrix and platelets, growth factors and cytokines. It is used for clinical and surgical applications which require hemostasis and tissue regeneration. Some fields in which it may be used are: periodontal, oral, maxillo-facial and plastic surgery, otorhinolaryngology, orthopedic and dermatology. PRF can be combined with other regenerative techniques. Areas of PRP application in dental medicine are: guided bone regeneration, guided tissue regeneration, revitalization of tooth with necrotic pulp and open apex and for healing of the soft tissue in periodontal plastic surgery.
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