Abstract
Platelet aggregability in 120 male patients with either Buerger's disease (TAO) or arteriosclerosis obliterans (ASO) was studied by optical density method. The results were compared with the clinical courses of the diseases. Hypoaggregability was observed with an addition of small amounts of ADP or collagen in TAO patients at the chronically aggravating and stationary stages. This hypoaggregability suggested to indicate some pathologic changes in vivo which may precede and promote thrombosis. Remarkably enhanced aggregability was noted in ASO patients at acute occlusive stage and in TAO patients at acute stage of thrombophlebitis migrans. Some differences in platelet aggregability between TAO and ASO were also discussed.
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