Abstract
Using the rotating glass bulb method it is shown that patients with cerebrovascular disease have platelets which are significantly more adhesive to glass than those of control subjects. Hyperadhesiveness is demonstrable within a day of cerebral infarction, and there is no evidence that it alters significantly within the first 6 weeks of infarction, or during a period of 6 months in established cerebral vascular disease. Platelet adhesiveness is independent of age and sex, as well as platelet count and the several other laboratory tests studied. Although there was no significant difference in mean platelet adhesiveness in patients and controls when stickiness was measured by the glass bead filter method, a good linear correlation was found between platelet adhesiveness values obtained by using the two methods simultaneously in 89 subjects.
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