Abstract
Navigated repetitive transcranial magnetic stimulation (nrTMS) Q2 24 is a novel technology that, unlike the other non-invasive methods 25 used to map language, applies a methodology (“virtual lesions”) 26 that is identical to that of the gold standard direct electrical stimu27 lation (DES) during awake surgery [1]. 28 The induction of brain plasticity due to pathological conditions 29 is an established observation and has been studied extensively 30 in stroke [2]. In brain tumor surgery, a small number of reports 31 have demonstrated that brain plasticity can occur in slow-growing 32 lesions and may enable the resection of tumors that were pre33 viously deemed inoperable due to their infiltration of areas that 34 carry essential language or motor function [3]. This article reports 35 for the first time a subacute reshaping of the language network 36 within 7 months after surgery for a left fronto-opercular glioblas37 toma detected by nrTMS. 38
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