Abstract
INTRODUCTION: Plasmodium vivax malaria represents a major public health problem. This study presents the quality assessment of clinical practice guidelines for the management of P. vivax malaria.METHODS: A systematic review was conducted in PubMed, SciELO, and Google Scholar. Additionally, five guidelines were assessed with the AGREE (Appraisal of Guidelines Research and Evaluation) II protocol.RESULTS The general performance on the domains of stakeholder involvement, development rigor, and editorial independence was low. CONCLUSIONS: Most guidelines lack a solid research methodology, which implies ambiguous accuracy. Much needs to be done in the area of therapeutics and quality of policies.
Highlights
Plasmodium vivax malaria represents a major public health problem
This study presents the quality assessment of clinical practice guidelines for the management of P. vivax malaria
A systematic review was conducted in PubMed, SciELO, and Google Scholar
Summary
This study presents the quality assessment of clinical practice guidelines for the management of P. vivax malaria. Data from in vitro CQ sensitivity studies in P. vivax report stage-specific effects of CQ, which raises more questions about antimalarial pharmacodynamics in P. vivax malaria, highlights the differences between these malaria species[3,9], and calls for the formulation of strategies to avoid the belief that established protocols cause a delayed response to resistance when CQ efficacy collapses.
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