Abstract
Plasminogen activator is a protease which catalyses the conversion of the inactive plasminogen to the active plasmin. Most transformed cell lines and solid tumors produce elevated levels of plasminogen activator compared with non-transformed counterparts. This increased synthesis of plasminogen activator may play a role in tumorigenesis, cancer invasion and metastasis. Measurement of plasminogen activator in tumor extracts and body fluids may provide diagnostic and prognostic information. Finally, since plasminogen activator is an estradiol-inducible enzyme, its measurement in breast carcinomas might be a marker for a functional estrogen receptor.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
