Abstract
1. 1. The enzyme kinetics for plasmalogenase have been analyzed on a developmental basis and correlated with the presence of ethanolamine plasmalogen (1-alkyl,1′-enyl,2-acyl-sn-glycerol-3-phosphoryl-ethanolamine) in dystrophic chicken erythrocyte membranes. 2. 2. At day 15 ex ovo, both dystrophic (Line 413) and normal (Line 412) chicken erythrocyte enriched microsomal preparations manifest high K m forms of plasmalogenase. 3. 3. However, with time, the K m of this enzyme from normal erythrocyte preparations drops significantly whereas the K m of the enzyme from dystrophic preparations remains high. 4. 4. This observation may account for elevated concentrations of plasmalogen observed in dystrophic chicken tissues.
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