Abstract
The plasmablastic lymphomas (PBLs) are an aggressive group of non-Hodgkin's lymphomas occurring primarily in human immunodeficiency virus (HIV)-infected individuals with absolute CD4 counts less than 200 per microliter. It was considered to be a diffuse large B-cell lymphoma with a unique im- munophenotype and occurred primarily in the oral cavity. Recent studies report that PBLs also occur in patients without HIV infection. Herein we report an unusual case of plasmablastic lymphoma presenting in nasal cavity in a 74-year-old, HIV-negative woman. Cytologic and histologic examinations demon- strated a large cell lymphoma with plasmacytic differentiation. The tumor cells were positive for CD79a, CD38, however lacked expression of leukocyte common antigen, T-cell, and B-cell markers. Epstein-Barr virus-encoded RNA transcripts were identified by in situ hybridization. To our best knowledge, this is the second case of plasmablastic lymphoma in HIV-negative patient in Korea. (Korean J Hematol 2009;44:122-126.)
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
