Abstract
Platelet-rich fibrin (PRF) is an autologous blood concentrate obtained without anticoagulants by centrifugation of patients’ peripheral venous blood. PRF is considered to enhance the formation of new bone. The aim of this manuscript was to present two case reports of permanent teeth with closed apexes with periapical lesions, treated endodontically with the use of PRF. The root canals were mechanically cleaned and shaped with NiTi files and irrigated with 5.25% sodium hypochlorite (NaOCl), 40% citric acid (CA), and triple distillated water. Before the canal systems were obturated, A-PRF was used as a scaffold and was placed below the cementodentinal junction with hand pluggers. Cone beam computerized tomography (CBCT) was used to assess the resolutions of periapical radiolucencies. After 6 months, the measurements of both periapical lesions were significantly reduced. Although the performed root canal treatments (RCTs) can definitely be recognized as successful, it must be emphasized that mechanical shaping and cleaning of the root canals with special disinfecting solutions significantly affect the clinical efficacy of RCT. It seems impossible to state that PRF played a leading role in the healing process of the presented periapical lesions. Further studies must be performed to assess whether RCT of mature teeth with an additional PRF application is superior to RCT performed alone.
Highlights
Root canal treatment (RCT) is performed to eliminate pulpal infection, which may be the consequence of severe caries lesions or non-carious conditions, including traumas
Four conditions have been found that significantly improve the final outcome of primary RCT, including lack of the periapical radiolucency, homogenous filling of the root canal system, filling of the root canal system that extends to 2 mm within the radiographic apex, and well-sealing post-endodontic restoration [1]
After the root canal was dried with paper cones, the freshly prepared A-Platelet-rich fibrin (PRF) membrane was placed into the apex and pushed below the the freshly prepared membrane was placed into the apex and pushed below freshly prepared membrane was placed into the apex and pushed below the level of the cementodentinal junction using Machtou hand pluggers—size 1/2 Nickel Titanium (NiTi) the level of cementodentinal the cementodentinal junction
Summary
Root canal treatment (RCT) is performed to eliminate pulpal infection, which may be the consequence of severe caries lesions or non-carious conditions, including traumas. Four conditions have been found that significantly improve the final outcome of primary RCT, including lack of the periapical radiolucency, homogenous filling of the root canal system, filling of the root canal system that extends to 2 mm within the radiographic apex, and well-sealing post-endodontic restoration [1]. The final outcomes of primary and secondary RCT are similar when the access to the apical infection is restored [2]. There is no evidence of data in the worldwide literature concerning the use of PRF in the endodontic treatment of mature permanent teeth with diagnosed chronic periapical periodontitis. The aim of this manuscript was to present two case reports of permanent teeth with closed apexes diagnosed with periapical lesions, treated endodontically with the use of PRF
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