Abstract

Scars are a common disfiguring sequela of various events such as acne, hidradenitis suppurativa, surgery, trauma, and burns, which can lead to serious psychosocial problems with a negative effect on the quality of life. Many conventional approaches have been proposed for the treatment of scars, including surgical techniques, dermabrasion, chemical peels, topical silicone gel, 5-fluorouracile and dermal fillers injection or autologous fat transfer for atrophic scars, and corticosteroids injection for hypertrophic and keloid scars; however, they have sporadic effects. Ablative lasers, such as carbon dioxide laser or Erbium Yag laser, are associated with many collateral effects limiting their application. Non-ablative laser treatments have been shown to be safer and to have fewer side effects, but they have a reduction of clinical efficacy compared to ablative lasers and a minimal improvement of scars. The demand for minimal invasive and safe technology for the treatment of a scars has stimulated the search for more effective novel therapy with fewer collateral effects. Plasma radiofrequency ablation is a new technique consisting of the generation of plasma energy through the production of ionized energy, which thermally heats tissue in a uniform and controlled manner, through a plasma radiofrequency device, inducing a sublimation of the tissue. The aim of this study is to evaluate the effectiveness of P-RF ablation in the treatment of scars performed with D.A.S. Medical device (Technolux, Italia), which is a tool working with the long-wave plasma radiofrequency principle.

Highlights

  • Scars are a common disfiguring sequela of various events such as acne, hidradenitis suppurativa, surgery, trauma, and burns, which can lead to serious psychosocial problems with a negative effect on the quality of life [1].Skin tissue repair results in a broad spectrum of scar types, ranging from “normal” fine line scars to abnormal scars, including stretched, atrophic, hypertrophic, keloid scars, and scar contractures [1].Abnormal healing processes can complicate the normal wound healing, resulting in the development of proliferative scars, such as hypertrophic scars and keloids, resulting from excessive deposition of collagen at sites of prior dermal injury or of wound repair due to an imbalance between collagen biosynthesis and matrix degradation [2]

  • Hypertrophic scars are raised scars that remain within the boundaries of the original lesions; keloid scars spread beyond the margins of the original lesions invading the surrounding normal skin [1]

  • Atrophic scars appear when dermal collagen and connective tissue production inadequately compensate for the tissue loss. They are depressed below the surrounding skin; small and round scars commonly arise after acne, hidradenitis suppurativa, or chickenpox

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Summary

Introduction

Scars are a common disfiguring sequela of various events such as acne, hidradenitis suppurativa, surgery, trauma, and burns, which can lead to serious psychosocial problems with a negative effect on the quality of life [1]. Abnormal healing processes can complicate the normal wound healing, resulting in the development of proliferative scars, such as hypertrophic scars and keloids, resulting from excessive deposition of collagen at sites of prior dermal injury or of wound repair due to an imbalance between collagen biosynthesis and matrix degradation [2]. Atrophic scars appear when dermal collagen and connective tissue production inadequately compensate for the tissue loss. They are depressed below the surrounding skin; small and round scars commonly arise after acne, hidradenitis suppurativa, or chickenpox

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