Abstract
Plasma-prolactin was assayed in 115 patients with breast cancer and 115 matched controls. Mean plasma-prolactin levels were 6.0 ± 3.7 ng. per ml. and 5.9 ± 2.9 ng. per ml., respectively. Plasma-prolactin levels were normally distributed in both groups. Plasma levels in 64 members of nine families with a high frequency of breast cancer were irregularly distributed, with a mean prolactin level of 10.4 ± 8.1 ng. per ml. Statistical evaluation demonstrated that breast-cancer patients and controls may be regarded as one population but that the prolactin levels in the high-risk group represent a different population (P < 0.0004).
Published Version
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