Abstract

ABSTRACT Plasma levels of progesterone (pregn-4-ene-3,20-dione) were measured in nineteen pregnant patients following intra-amniotic injection of hypertonic saline between the 13th and 20th week of gestation. A significant decrease in the plasma progesterone was found 5, 10, and 24 hours following the injection. However, the decrease in plasma progesterone was not correlated to the time interval between the saline-injection and the onset of clinical labour (correlation coefficient 0.019).

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