Abstract
Aim: Proprotein convertase subtilisin/kexin 9 (PCSK9), a protein regulating the number of cell-surface low-density lipoprotein (LDL) receptors (LDL-R), circulates partially associated to LDL, high-density lipoproteins (HDL) and lipoprotein (a). How this interaction alters PCSK9 plasma levels is still unclear. In the present study, we investigated whether a condition of familial hypoalphalipoproteinemia (FHA), due to genetic mutations in LCAT, ABCA1 or APOAI genes, could alter PCSK9 levels and distribution among different lipoproteins.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
