Plasma Lycopene Is Associated with Pizza and Pasta Consumption in Middle-Aged and Older African American and White Adults in the Southeastern USA in a Cross-Sectional Study.

Yuan E Zhou,William J Blot,David G Schlundt,Maciej S Buchowski,Margaret K Hargreaves,Jianguo Liu,Flora A M Ukoli,Zhuo Zhang

doi:10.1371/journal.pone.0161918

Yuan E Zhou, William J Blot + Show 6 more

Open Access

https://doi.org/10.1371/journal.pone.0161918

Copy DOI

Journal: PloS one	Publication Date: Sep 1, 2016
Citations: 12	License type: CC BY 4.0

Affiliation: Meharry Medical College, Vanderbilt University

Abstract

BackgroundThe role of dietary lycopene in chronic disease prevention is not well known.MethodsThis study examined intake of lycopene and other antioxidants from lycopene-rich foods (e.g., pizza and pasta) simultaneously with plasma levels of lycopene and other antioxidants in a representative cross-sectional sample (187 Blacks, 182 Whites, 40–79 years old) from the Southern Community Cohort Study (SCCS). The SCCS is an ongoing study conducted in populations at high risk for chronic diseases living in Southeastern United States. Dietary intake was assessed using a validated food frequency questionnaire (FFQ), and plasma levels of lycopene and other antioxidants were measured at baseline (2002–2005). The participants were classified into tertiles according to consumption of pizza and pasta food groups.ResultsLycopene dietary intake and plasma lycopene concentrations were significantly higher in the highest (tertile 3) compared to tertiles 1 and 2 (both P < 0.01). Total energy intake ranged from 1964.3 ± 117.1 kcal/day (tertile 1) to 3277.7 ± 115.8 kcal/day (tertile 3) (P<0.0001). After adjusting for age and energy intake, total dietary fat, saturated fatty acids, trans-fatty acids, and sodium intakes were significantly higher in tertile 3 than tertiles 2 and 1 (all P <0.01). Vitamin C intake was significantly lower in tertile 3 than tertiles 1 and 2 (P = 0.003). Except for γ-tocopherol being higher in tertile 3 than tertiles 1 and 2 (P = 0.015), the plasma concentrations of antioxidants were lower in tertile 3 than tertiles 1 and 2 (β-carotene, α-carotene, lutein and zeaxanthin, all P<0.05).ConclusionsIn the SCCS population, pizza and pasta were the main sources of dietary lycopene and their intake was associated with plasma lycopene concentration. Diets with frequent pizza and pasta consumption were high in energy, saturated fatty acids, trans-fatty acids, sodium and low in other antioxidants. Future studies of lycopene as a protective dietary factor against chronic disease should consider the overall nutritional quality of lycopene-containing foods.

Highlights

Lycopene is one of the major plant food carotenoids [1]
In the Southern Community Cohort Study (SCCS) population, pizza and pasta were the main sources of dietary lycopene and their intake was associated with plasma lycopene concentration
Diets with frequent pizza and pasta consumption were high in energy, saturated fatty acids, trans-fatty acids, sodium and low in other antioxidants

Summary

Introduction

Lycopene is one of the major plant food carotenoids [1] It is a potent antioxidant with the strongest single oxygen quenching capacity among the carotenoids in vitro [2] and it is believed to mitigate oxidative stress effects on cells in vivo [3]. In the United States, tomatoes and tomato-based foods are the major dietary sources of lycopene [8]. Lycopene’s bioavailability is improved by food processing, including mechanical or heat disruption of the plant cells and extraction of lycopene into the lipophilic phase in commonly used products such as tomato sauces and ketchup [9, 10]. The role of dietary lycopene in chronic disease prevention is not well known

Objectives

Methods

Results

Conclusion