Abstract
ABSTRACTDuring pregnancy in twelve bitches a significant increase was observed in the circulating activity of the specific coagulation factors VII, VIII, IX and XI. Such changes did not occur in two bitches which were bred but did not conceive. Comparison of the plasma procoagulant activity and oestradiol‐17β levels indicated that alterations in the coagulation factor activity may, at least in part, be mediated by the changes in oestrogen levels which occur in the pregnant bitch.
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