Plasma induced cytocompatibility of stabilized poly-L-lactic acid doped with graphene nanoplatelets

Abstract

The process of preparation, optimization and volume doping of thin poly-L-lactide acid foils is described in this paper. The goal of the doping is to improve overall properties as well as surface nanostructures construction by consequent plasma treatment. The next step of surface enhancement of graphene doped foils involved argon plasma treatment or combination of plasma and heat treatment. The certain combination of plasma treatment and graphene nanoplatelets doping increased the cytocompatibility of PLLA surface for vascular smooth muscle cells significantly. This result is also important for possible electrical stimulation of neuron or other cell types, which would proliferate on biopolymer and for construction of several types of biopolymer sensors based on conductivity measurement, yet prepared on eco-friendly biopolymer basis.