Abstract
ABSTRACT The researchers studied the correlation of Haptoglobin (HP) and Group-specific Component (GC) plasma protein biomarkers in chronic kidney disease (CKD) patients and non-CKD controls using discontinuous-polyacrylamide gel electrophoresis. The results showed a significant difference between the CKD and control clusters of 2-2 variants for HP (p=0.0036) and GC (p= 0.0033). The current research indicates 2-2 phenotype is an independent risk determinant for CKD, while risk analysis reports odds value >1 for both protein polymorphisms signifying an effective risk towards CKD. The multifactor dimensional reduction analysis also detailed HP and GC markers have a strengthening and stronger association and are causative for CKD development. Collectively, the findings signify a potential risk of plasma HP and GC polymorphisms being susceptible to CKD and their key role in the deterioration of kidney functions.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
