Abstract
Abstract In order to determine whether 5-methoxypsoralen (5-MOP) (which bears resemblance to serotonin) restores the circadian rhythm of plasma 3-methoxy-4-hydroxyphenylglycol (MHPG), the metabolite of noradrenaline (NA), plasma free MHPG, was analyzed in blood samples obtained every hour over 24 h for six sleep-deprived healthy subjects, three of whom had taken 5-MOP the previous evening. Although 5-MOP had no demonstrable effect on the plasma NA circadian rhythm in a previous study, it may preserve a weak free MHPG circadian rhythm, by preventing the nocturnal increase in MHPG.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
