Abstract
SummaryThe rate of plasma disappearance of 125I-labeled highly purified human urinary erythropoietin (ESF) was compared with that of unlabeled partially purified human urinary ESF in anesthetized rabbits. Plasma T1/2 values for both the labeled and unlabeled ESF were essentially biphasic. The mean half-time disappearance of 125I-labeled ESF was 35.87 min for the rapid phase and 10.25 hr for the slow phase. The half-time disappearances of the unlabeled ESF for the rapid and slow phases were 32.39 min and 7.98 hr, respectively. The T1/2 values of the 125I-labeled ESF and the unlabeled ESF are not significantly different.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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