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Abstract
Abstract Male Long-Evans rats were conditioned to lever press for water on a continuous reinforcement schedule. Plasma corticosterone concentrations were determined following reinforced sessions and extinction sessions. All animals were sampled under both conditions, using a balanced repeated measures design. In addition, the pre-session or basal concentration of plasma corticosterone was measured in one subgroup. Plasma corticosterone levels were significantly elevated as a function of extinction, while reinforced responding produced no change compared to the basal level. The results show a major physiological change occurring as a consequence of extinction of an appetitive task; this and other findings suggest that the pituitary-adrenal hormone system plays a role in extinction of appetitive behavior.
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