Abstract
This contribution reviews our work on the fabrication of surfaces containing specific chemical functional groups by means of plasma copolymerization and their use as substrata for cell culture. The methodology of plasma copolymerization is detailed for acrylic acid with 1,7-octadiene. X-ray photoelectron spectroscopy (XPS) has been employed to analyse the plasma copolymers produced from these monomers. A number of different cell types (keratinocyte, endothelial and osteoblast-like) have been cultured upon plasma copolymer surfaces containing 3–6% carboxyl (3–6 carboxyls per 100 carbons). The data reported demonstrate the potential of plasma copolymer surfaces as substrata for cell culture.
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