Plasma Cell Mucositis of the Vagina

Abstract

Plasma cell mucositis is a rare dermatologic condition known to affect the upper aerodigestive tract and external genitalia but has never yet been described to affect the vaginal epithelium. A 57-year-old woman presented to the urogynecology clinic with chief complaint of symptomatic pelvic organ prolapse and vaginal spotting. Examination of the pelvis revealed grade 2 pelvic organ prolapse and diffuse multifocal erythematous patches on the vaginal introitus, vagina, cervix, and periurethra. Histopathologic examination of biopsies revealed plasma cell mucositis. This is the first report of plasma cell mucositis affecting vaginal epithelium. It is possible that pelvic organ prolapse caused irritation and inflammation of vaginal epithelium and contributed to the development of plasma cell mucositis in these areas.