Abstract

Plasma cell gingivitis features a distinctive and rare pattern of gingival inflammation characterized by infiltration of plasma cells in the oral tissues with unknown reason or generally related to an allergen. A 20-year-old female patient attended a surgery service, showing a generalized and painless enlargement of gingiva, with a discrete erythema. She did not have any systemic disease and was not on medication. There was a previous excisional biopsy with an inconclusive diagnosis. The lesion resurged in 3 months, and a new biopsy in the posterior gingiva was then performed with a hypothesis of gingival hyperplasia. Histopathology revealed fibrous connective tissue characterized by deposition of collagenous fibers and intense chronic inflammatory infiltrate predominantly composed of plasma cells but also lymphocytes and eosinophils. The diagnosis of plasma cell gingivitis was then established. Several recommendations were given to the patient in relation to her eating habits and allergen possibilities.

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