Abstract
The effects of short-term steroid treatment on the blood and pituitary LH and FSH levels of previously castrated adult male and female rats were examined, using ovarian ascorbic acid depletion (OAAD) and HCG-augmentation bioassays for LH and FSH activities. Pituitary and plasma FSH activities, 3 days after an injection of 1) testosterone propionate (TP) or 2) estradiol benzoate plus progesterone (E + P), were compared in 5 experiments. Concomitant changes in plasma and pituitary LH levels were studied in 3 of these experiments and 2 others. In 2 further studies in spayed rats, both stored and circulating LH and FSH were examined after 7 days of TP treatment. In addition, pituitary FSH and plasma LH were studied 24 hr after single injections of TP. Both steroid treatments (TP and E + P) decreased plasma LH levels without altering pituitary LH concentrations detectably. The TP effect on plasma LH was evident after only 24 hr. Thus, both treatments apparently reduced the rate of LH release. Because of the re...
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
