Abstract
AimWe assessed the correlation between plasma adiponectin levels and carotid intima media thickness (IMT), as a marker of atherosclerosis, in non-obese patients with type 2 diabetes. MethodsThe study group included 112 (60 males and 52 females) non-obese Egyptian patients with type 2 diabetes. Fasting plasma adiponectin was measured using ELISA technique. Carotid IMT was assessed using high-resolution color- coded Doppler ultrasonography. Forty age, sex and weight matched normal Egyptian subjects were included in the study as a control group. ResultsA non-significant inverse correlation was found between plasma adiponectin levels and carotid IMT in the study group (p=0.054). Multiple regression analysis revealed that plasma adiponectin was not a determinant of carotid IMT in the study group (p=0.061). ConclusionThe inverse relation between plasma adiponectin and carotid IMT in type 2 diabetes could be explained, at least partially, by obesity.
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