Abstract
Abstract— The plaque‐inhibiting effect of three commercial toothpastes and three test toothpastes was tested in a series of clinical trials. Cap splint applicators were used to avoid the effect of toothbrushing and the test persons teeth were rinsed with sucrose during the experimental periods to provoke plaque formation. Two of the test dentifrices which contained chlorhexidine digluconate (0.6 % and 0.8 % respectively) reduced plaque formation. In some individuals a certain plaque inhibition was observed also by the commercial dentifrices tested. The chlorhexidine‐containing toothpastes showed stronger antibacterial activity against salivary bacteria in vitro than the commercial dentifrices. It is concluded that the method used for testing the plaque‐inhibiting effect of dentifrices may be useful, and that it is possible to maintain the plaque‐inhibiting effect of chlorhexidine previously described in several mouthrinse experiments when a toothpaste is used as a vehicle for the agent.
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