Abstract
Hypertension is a critical health problem and worse other cardiovascular diseases. It is mainly of two types: Primary or essential hypertension and Secondary hypertension. Hypertension is the primary possibility feature for coronary heart disease, stroke and renal vascular disease. Herbal medicines have been used for millions of years for the management and treatment of hypertension with minimum side effects. Over aim to write this review is to collect information on the anti-hypertensive effects of natural herbs in animal studies and human involvement as well as to recapitulate the underlying mechanisms, from the bottom of cell culture and ex-vivo tissue data. According to WHO, natural herbs/shrubs are widely used in increasing order to treat almost all the ailments of the human body. Plants are the regular industrial units for the invention of chemical constituents, they used as immunity booster to enhance the natural capacity of the body to fight against different health problems as well as herbal medicines and food products also. Eighty percent population of the world (around 5.6 billion people) consume medicines from natural plants for major health concerns. This review provides a bird’s eye analysis primarily on the traditional utilization, phytochemical constituents and pharmacological values of medicinal herbs used to normalize hypertension i.e. Hibiscus sabdariffa, Allium sativum, Andrographis paniculata, Apium graveolens, Bidenspilosa, Camellia sinensis, Coptis chinensis, Coriandrum sativum, Crataegus spp., Crocus sativus, Cymbopogon citrates, Nigella sativa, Panax ginseng,Salviaemiltiorrhizae, Zingiber officinale, Tribulus terrestris, Rauwolfiaserpentina, Terminalia arjuna etc.Graphic
Highlights
Hypertension is a serious medical condition and can increase the risk of heart, brain, kidney and other diseases
This review provides a bird’s eye analysis primarily on the traditional utilization, phytochemical constituents and pharmacological values of medicinal herbs used to normalize hypertension [13, 14]
It is the most important to search the more effective way to treat hypertension and cardiovascular diseases (CVDs) that is the prime cause of death, globally
Summary
Pathophysiology of hypertensionand and treatment: Genetic Factors + Environmental Factors. Antioxident/ ROS scavenging Camellia sinensis, Zingiber officinale, Terminalia arjuna. ACE Inhibitors Nigella sativa, Endothelium Tribulus terrestris dependent/Independent pathway Hibiscus sabdariffa, Crataegus spp. Enhance NO Production and Release Allium sativum, Tribulus terrestris, Andrographis paniculata, Camellia sinensis, Panax ginseng. Keywords Hypertension · Antihypertensive herbs · Blood pressure · Vasodilatation · Herbal medicines · Blood pressure regulation
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