Abstract

Guggulu , a r esin from Com m iphora mukul is an established anti - inflammatory agent since ancient time . It has been first describe d in Atharva Veda in 2000 B . C . Guggulu is the dry gum resin obtained from the bark of the Commiphora mukul . Phy to - chemically it is found to be mixture of diterpenes, sterols, steroids, esters and higher alcohols . Topical application of Guggulu resin as anti - inflammatory agents at the site of inflammation is a proven effective measure for the arthropathies & various other musculo - skeletal conditions . Since most of the drugs showed less than adequate skin permeability , so the iontophoresis an electrically - assisted trans - dermal drug delivery system ” was proposed to be a physical technique for enhancement of skin perme ation of topical drugs . Plantar fasciitis is a common cause of heel pain in adults with the peak incidence occurring in people between the ages of 40 – 60 yeas . Various treatment modalities have been proposed but with debatable outcome . So an effort has b een made to execute plantar iontophoresis using aqueous solution of Guggulu resin in the management of plantar fasciitis .

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