Abstract

Plant molecular pharming has emerged as a reliable platform for recombinant protein expression providing a safe and low-cost alternative to bacterial and mammalian cells-based systems. Simultaneously, plant viruses have evolved from pathogens to molecular tools for recombinant protein expression, chimaeric viral vaccine production, and lately, as nanoagents for drug delivery. This review summarizes the genesis of viral vectors and agroinfection, the development of non-enveloped viruses for various biotechnological applications, and the on-going research on enveloped plant viruses.

Highlights

  • Reviewed by: George Peter Lomonossoff, John Innes Centre (JIC), United Kingdom Zhenghe Li, Zhejiang University, China Ulrich Commandeur, RWTH Aachen University, Germany

  • This review summarizes the genesis of viral vectors and agroinfection, the development of non-enveloped viruses for various biotechnological applications, and the on-going research on enveloped plant viruses

  • This pathogen is known as tobacco mosaic virus (TMV) and is one of the prominent viruses in plant molecular pharming

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Summary

Introduction

Reviewed by: George Peter Lomonossoff, John Innes Centre (JIC), United Kingdom Zhenghe Li, Zhejiang University, China Ulrich Commandeur, RWTH Aachen University, Germany.

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