Year-end Sale % OFF 
Abstract
Functional homologous and non-homologous clusters of MIR genes that co-regulate target mRNA transcripts have been identified in plants
Highlights
MicroRNAs are endogenous single-stranded small RNAs that regulate the expression of specific mRNAs involved in diverse biological processes
MicroRNAs are endogenous approximately 21nucleotide single-stranded small RNAs derived from MIRNA precursors that are able to fold-back into a stable secondary structure. miRNAs act in many developmental processes as well as environmental and pathogenic responses [1,2,3,4] through the post-transcriptional regulation of target mRNAs
In silico identification of miRNA clusters in Arabidopsis, rice and poplar genomes A systematic search for consecutive MIRNA loci was carried out in three model plant genomes that have an exhaustive description of their miRNA species
Summary
MicroRNAs (miRNAs) are endogenous single-stranded small RNAs that regulate the expression of specific mRNAs involved in diverse biological processes. MiRNAs act in many developmental processes as well as environmental and pathogenic responses [1,2,3,4] through the post-transcriptional regulation of target mRNAs. MicroRNAs (miRNAs) are endogenous approximately 21nucleotide single-stranded small RNAs derived from MIRNA precursors that are able to fold-back into a stable secondary structure (stem loop or hairpin). Formation of an approximately 21-bp miRNA-miRNA* duplex successively involves two RNase III enzymatic complexes: the Drosha enzyme, which cleaves long pri-MIRNA in the nucleus to generate short (approximately 70- to 80-nucleotide) hairpins (so called pre-MIRNA) and the Dicer enzyme, which produces the miRNA after cytoplasmic export of pre-MIRNAs through Exportin 5 [11] In plants, both cleavages are likely nuclear localized and involve a single Dicer-like enzyme 1 (DCL1) complex [6,9,10]. The miRNAs guide sequence-specific cleavage and/or translational repression of target transcripts into the RISC complex [6,911]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
