Abstract
The mosquito species Aedes aegypti is one of the main vectors of arboviruses, including dengue, Zika and chikungunya. Considering the deficiency or absence of vaccines to prevent these diseases, vector control remains an important strategy. The use of plant natural product-based insecticides constitutes an alternative to chemical insecticides as they are degraded more easily and are less harmful to the environment, not to mention their lower toxicity to non-target insects. This review details plant species and their secondary metabolites that have demonstrated insecticidal properties (ovicidal, larvicidal, pupicidal, adulticidal, repellent and ovipositional effects) against the mosquito, together with their mechanisms of action. In particular, essential oils and some of their chemical constituents such as terpenoids and phenylpropanoids offer distinct advantages. Thiophenes, amides and alkaloids also possess high larvicidal and adulticidal activities, adding to the wealth of plant natural products with potential in vector control applications.
Highlights
The mosquito Aedes aegypti (Diptera: Culicidae) originated in Egypt and it is widely distributed in tropical and subtropical regions, including North America and Europe [1,2]
Essential oils are obtained by steam distillation or of active compounds include terpenes, alkaloids and amides, steroids, flavonoids, furanochromones, hydrodistillation
Than the ethanolic extract (LC50 75.45 μg/mL). This result suggests that the constituents of the essential oil either exhibit higher larvicidal activity, or that the synergy between them favors the toxicity to the mosquito [60]
Summary
The mosquito Aedes aegypti (Diptera: Culicidae) originated in Egypt and it is widely distributed in tropical and subtropical regions, including North America and Europe [1,2]. In 2012, dengue was considered the mosquito-borne disease of major importance in the world [5]. According to the World Health Organization, 390 million people are infected annually with the dengue virus, 96 million of which have clinical manifestations [6]. There is no specific treatment for dengue and the more complicated cases of the disease can cause hemorrhage, shock and even death [7]. There is no specific treatment for dengue and the more complicated cases of the disease can cause hemorrhage, shock. Ae. aegypti is considered the main Zika virus vector (Figure 1), but infection can occur by sexual or blood transfusion [8]. 1), but and infection can occur by confused with other diseases.[8] Some important exist, such as microcephaly sexual transmission orarboviral blood transfusion.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
