Abstract
Gingival enlargement is an inflammatory response to plaque present on tooth surfaces or due to factors like drugs and several systemic conditions. In cases where the local factors are responsible and subgingival scaling and root planing do not help, gingivectomy/gingivoplasty is performed which creates a raw wound which heals slowly. Since surgical practice primarily depends upon the healing of these wounds without serious complication and infection occurring, to increase the rate of healing of a postoperative surgical wound, placental extract gel has been used as a therapeutic agent because it has unique pharmacological effects like enhancement of wound-healing, anti-inflammatory action, analgesic effect etc. A variety of substances with biological and therapeutic activity present in human placenta have been isolated and identified as hormones, proteins, glycosaminoglycans, nucleic acids, polydeoxyribonucleotides (PDRNs) etc. which therefore play a major role in the faster healing of a surgical wound.
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