Abstract
Aim of the study - the analysis of the current understanding of local changes in the mucous membrane of PNS in AS, as well as methods of pharmacotherapy of the disease. The authors consider the main mechanisms of pathogenesis of both acute and chronic sinusitis. One of the reasons underlying the development of infectious inflammation is described in detail: disturbance of drainage function of paranasal sinuses, aeration, mucociliary transport. Analytical evaluation of modern means of rational pharmacotherapy was made. It is concluded that the use of mucolytic drugs improves treatment results.
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