PL-009 Interferon and nucleoside/tide analog reduce risk of hepato-cellular carcinoma among hepatitis B patients: a meta-analysis

Abstract

136 staphylococci was 94.8% (129/136) accordance with the phenotype results and 100% accordance with the sequencing results. Staphylococci were identified to common macrolides resistance genes and the positive probability was 75.7% (103/136). The results of 110 Escherichia coli and 94 Klebsiella pneumoniae was 97.1% (198/204) accordance with the phenotype results and 100% accordance with sequencing results. Common beta-lactamases resistance genes positive probability were 42.7% (47/110) in Escherichia coli and 36.2% (34/94) in Klebsiella pneumoniae. Conclusion Multiplex real-time SYBR Green I PCR combining melt temperature assay can screen rapidly and identify accurately common macrolides resistance genes in staphylococci and beta-lactamases resistance genes in Escherichia coli or Klebsiella pneumoniae. The multiple detection platform can be applied to detect common resistance genes in clinical specimen and the method has important value in instructing clinician to prescribe accurate antibiotics and monitoring for resistance epidemiology.