Abstract
The analysis of copper, iron, calcium, and other elements in livers of Long-Evans Cinnamon(LEC) rats by PIXE determination is described. The copper contents in the livers of LEC rats which were supplemented with 1g/100g, in the food of calcium chloride dihydrate and iron(II) chloride n-hydrate, respectively, for 5 weeks were determined before and after supplement by PIXE. The experimental results showed that after supplement of the calcium- and iron-fortified food the copper content in the livers of LEC rats decreased with the supplement. The present data suggest that supplement of iron or calcium can be responsible for copper homeostasis in livers of LEC rats, and that the excessive accumulation of copper in livers of LEC rats can readily remove when high load of iron or calcium are supplemented.
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