Abstract
Pituitary non-functioning macroadenomas: If and when to recommend surgery
Highlights
Pituitary non-functioning adenomas may be detected based on pituitary insufficiency, hyperprolactiemia, visual field complications or headache, etc, so called pituitary mass syndrome [1,2,3]
Pituitary incidentaloma have less than 1 cm diameter and they have a prevalence of 10% in previously unselected cases [4,5,6]
The non-functioning pituitary macro-adenoma are rarer than microadenomas and they may be accidentally detected or based on local complications [11]
Summary
Pituitary non-functioning adenomas may be detected based on pituitary insufficiency, hyperprolactiemia, visual field complications or headache, etc, so called pituitary mass syndrome [1,2,3]. Pituitary incidentaloma have less than 1 cm diameter and they have a prevalence of 10% in previously unselected cases [4,5,6]. The most frequent secretor pattern of a pituitary adenoma is non-secretor while the most secretion, if any, is of prolactin [3,7,8]. Somatotropinoma and corticotropinoma are rarer and typically this types of tumour is associated with a specific phenotype, independent of pituitary mass syndrome [9,10]. The non-functioning pituitary macro-adenoma are rarer than microadenomas and they may be accidentally detected or based on local complications [11]
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