Abstract

It has been reported from several sources1, 2, 3 that glycosuria was obtained after the injection of anterior pituitary extract. Houssay4 reports that daily injections of the extract into dogs cause hyperglycemia, glycosuria and ketonuria. Evans, et al.,5 observed glycosuria in 2 dogs treated with growth hormone. Barnes, Regan, Nelson6 found that Amniotin injections reduced glycosuria in depancreatized dogs. Houssay and Biasotti7 injected rats with the Evans and Simpson extract for growth. Five to 7 injections were given, intraperitoneally, once a day in doses of 10 cc. per rat. Glycosuria and glycemia occurred 2 to 3 days after the cessation of the injections.In view of these researches it was thought worth while to try the effect of the various pituitary hormones upon the blood sugar level of the rat. Growth hormone (Squibb); pregnancy urine extract, Antuitrin S (Parke-Davis); theelin (Parke-Davis) and Antuitrin G (Parke-Davis Growth Hormone) were used. All the determinations were made by the Somogyi Mi...

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