PITUITARY GONADOTROPINS IN GONADAL DYSGENESIS

Abstract

Four prepubertal girls with gonadal dysgenesis whose urine contained pituitary gonadotropin have been studied at various ages at the University of California Medical Center; considerable variation in urinary gonadotropin has been noted in three. Urinary gonadotropin levels should be determined in each case where the diagnosis of gonadal dysgenesis is entertained. More than a single 24-hour specimen of urine should be tested, as a single negative specimen may be followed by one containing a diagnostically significant amount of gonadotropic activity. [See FIG. 1. in Source Pdf.]