Abstract

 CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
 The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
 This review assesses Pitolisant hydrochloride (Wakix), up to 40 mg daily, 5 mg and 20 mg tablets, oral.
 Indication: Treatment of excessive daytime sleepiness or cataplexy in adults with narcolepsy.
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